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Core Modules

The Program consists of 7 modules with theoretical background on genetics and molecular pathology of disease:

  • Human Genetics
  • Functional Genomics
  • Developmental Genetics
  • Infections and Immune Response
  • Cardiovascular Disease and Pharmacology
  • Molecular Mechanisms of Cancer Disease
  • Maintenance and Integrity of the Endocrine System

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Human Genetics (5 ECTS)

The aim of this module is to understand the molecular basics of human genetics, mutation mechanism and hereditary diseases. The module includes topics like mechanisms of hereditary, human cytogenetic and prenatal diagnosis, molecular mechanisms of tumor diseases, methods for identifying disease-relevant genes and evaluation of mutations, the use of data bases, as well as ethical aspects related to the application of human genetics.

Module Coordinator: PD Dr. Dominik Seelow (Charité, Neurocure Clinical Research Centre)

Functional Genomics (10 ECTS)

This module is divided into three sections; Bioinformatics; High throughput technologies and systems biology; and Population Genetics. Specific topics covered include genomes and statistics, transcriptomics, and proteomics. The laboratory portion of the module consists of computer exercises, some of which students conduct individually, others of which are conducted in small groups, or by the group as a whole.

Module Coordinator: Prof. Dr. Hans-Peter Herzel (HU Berlin, Institute for Theoretical Biology)

Developmental Genetics (5 ECTS)

Developmental genetics is the study of how genes control the growth and development of an organism throughout its life-cycle. This module teaches students about vertebrate development before birth, including organogenesis, genetic functional analysis in different animal models, and the theoretical basics of stem cell biology and regenerative medicine.

Module Coordinator: Prof. Dr. Bernhard Hermann (Max-Planck-Institute for Molecular Genetics)

Infections and Immune Response (7.5 ECTS)

Here students concentrate on the molecular basis of interactions between pathogens and their hosts, as well as epidemiology. Also molecular basics of virology, bacteriology and parasitology are part of this module so is the immunology of infections.

Module Coordinator:  Prof. Dr. Günther Schönrich (Charité, Institute for Virology)

Cardiovascular Disease and Pharmacology (7.5 ECTS)

This module covers the cellular and molecular mechanism of the development and progression of cardiovascular diseases and the basic principles of the therapeutic intervention of these diseases. This includes topics like anatomy and physiology of the heart, heart development, genetic of cardiovascular disorders, cardiac hypertrophy, atherosclerosis, gender specific aspects and the molecular pharmacology of the cardiovascular system.

Module Coordinator:  PD Antje Ludwig (Charité, Center for Cardiovascular Research)

Molecular Mechanisms of Cancer Disease (7.5 ECTS)

This module aims to provide the theoretical knowledge and experience of cellular and molecular biology and their application to human cancer. The course will focus on oncogenic signal transduction, angiogenesis, apoptosis, cell cycle regulation, selected tumor diseases like hematologic and solid tumors and its clinical demonstration, tumor immunology.

Module Coordinator:  Prof. Dr. Ulrike Stein (Max-Delbrueck-Centre for Molecular Medicine, Translational Oncology)

Maintenance and Integrity of the Endocrine System (7.5 ECTS)

This module teaches the fundamental background of endocrinology and the potency and limitations of endocrine analysis. Further topics are feedback regulation, human ductless glands, hormone classes, biochemistry of hormone receptors, inherent endocrine diseases, endogenous rhythm and the gender differences.

Module Coordinator:  Prof. Dr. Lutz Schomburg (Charité, Institute for Experimental Endocrinoloy)